ITGA2B Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22101-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22101-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22101-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22101-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:5D1
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CD41
Background:
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-200
Immunogen:
Synthetic Peptide
Purification method:
Protein A purification
Target Synonym:
antigen CD41;BDPLT16;BDPLT2;CD41;CD41B;form 2;GP2B;GPalpha IIb;GPIIb;GT;GTA;HPA3;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;Integrin;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;antigen CD41);ITA2B;Itga2b;ITGAB;platelet fibrinogen receptor;alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;Platelet membrane glycoprotein IIb;platelet specific antigen BAK;PPP1R93
UNIProt ID:
P08514