MGMT Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40155-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40155-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40155-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40155-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MGMT
Background:
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
22 kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant human Methylated DNA protein cysteine methyltransferase protein
ObservedMW:
22 kDa
Purification method:
Affinity purification
Target Synonym:
6 O methylguanine DNA methyltransferase;6-O-methylguanine-DNA methyltransferase;Agat;AGT;AI267024;EC 2.1.1.63;Methylated DNA protein cysteine methyltransferase;Methylated-DNA--protein-cysteine methyltransferase;Methylguanine DNA methyltransferase;MGC107020;MGMT;MGMT;O 6 methylguanine DNA alkyltransferase;O 6 methylguanine DNA methyltransferase;O-6-methylguanine-DNA methyltransferase;O-6-methylguanine-DNA-alkyltransferase
UNIProt ID:
P16455