Recombinant Human GH1/Growth hormone 1 Protein (Active)
| Code | Size | Price |
|---|
| PKSH030498-50ug | 50ug | £615.00 |
Quantity:
| PKSH030498-1mg | 1mg | £4,999.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Cell Culture
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
GH1;Growth hormone 1
Accession:
P01241
Activity:
Measured by its ability to promote proliferation of INS-1 cells. The ED50 for this effect is 0.2-1 ng/mL.
Background:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene; along with four other related genes; is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones; leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Calculated MW:
22.1 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Phe27-Phe217
Target Synonym:
GH;GH-N;GH1;GHB5;GHN;Growth hormone 1;hGH-N;IGHD1B
UNIProt ID:
P01241