Recombinant Human FGF8a/FGF-8a Protein (Active)
| Code | Size | Price |
|---|
| PKSH030497-50ug | 50ug | £574.00 |
Quantity:
| PKSH030497-1mg | 1mg | £4,999.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Cell Culture
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Further Information
Abbreviation:
FGF8a;FGF-8a
Accession:
NP_149355.1
Activity:
Measured in a cell proliferation assay using BALB/C-3T3 mouse fibroblasts. The ED50 for this effect is typically 0.8-3. 3 ug/mL.
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Calculated MW:
21.3 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln23-Arg204
Target Synonym:
AIGF;FGF-8;HBGF-8;HH6;KAL6