Recombinant Human CD3E & CD3G Heterodimer Protein (Active)

Elabscience
Product Code: PKSH030476
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH030476-50ug50ug£924.00
Quantity:
PKSH030476-500ug500ug£4,999.00
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Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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Further Information

Abbreviation:
CD3E & CD3G Heterodimer
Accession:
NP_000724.1&NP_000064.1
Activity:
Measured by its ability to bind OKT3-mIgG2a in a functional ELISA.
Background:
T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Calculated MW:
77.2 (40.1+37.1) kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-hFc-Flag & mFc Tag
ObservedMW:
42-47 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Asp126&Met1-Ser116
Target Synonym:
CD3E;CD3G Heterodimer;IMD18;T3E;TCRE