14-3-3 epsilon Polyclonal Antibody

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Elabscience
Product Code: E-AB-12585
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-12585-20uL20uL£125.00
Quantity:
E-AB-12585-60uL60uL£172.00
Quantity:
E-AB-12585-120uL120uL£237.00
Quantity:
E-AB-12585-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human brain malignant glioma and laryngocarcinoma tissue using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:1300
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Immunohistochemistry of paraffin-embedded Human colon cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60
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Immunohistochemistry of paraffin-embedded Human ovarian cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60
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Western Blot analysis of Human brain malignant glioma and laryngocarcinoma tissue using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:1300
Immunohistochemistry of paraffin-embedded Human colon cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human ovarian cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60

Documents

Further Information

Abbreviation:
YWHAE
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
29kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human YWHAE
Purification method:
Affinity purification
Target Synonym:
14 3 3 E;14 3 3 epsilon;14 3 3E;14-3-3 protein epsilon;14-3-3E;1433E;Epididymis luminal protein 2;FLJ45465;FLJ53559;HEL2;KCIP 1;KCIP1;MDCR;MDS;Mitochondrial import stimulation factor L subunit;Protein kinase C inhibitor protein1;Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein;epsilon;Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein;epsilon polypeptide;Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide;YWHAE
UNIProt ID:
P62258