XRCC4 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22044-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22044-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22044-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22044-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:8K2
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
XRCC4
Background:
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
38kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Immunogen:
Synthetic Peptide
ObservedMW:
38kDa
Purification method:
Protein A purification
Target Synonym:
DNA double strand break repair and V(D)J recombination protein XRCC4;DNA repair protein XRCC4;SSMED;X ray repair complementing defective repair in Chinese hamster cells 4;X ray repair cross complementing 4;X ray repair cross complementing protein 4;X-ray repair cross-complementing protein 4;XRCC 4;XRCC4;XRCC4
UNIProt ID:
Q13426