USP2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10878-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10878-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10878-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10878-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
USP2
Background:
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human USP2
Purification method:
Affinity purification
Target Synonym:
41 kDa ubiquitin specific protease;41 kDa ubiquitin-specific protease;Deubiquitinating enzyme 2;Ubiquitin carboxyl terminal hydrolase 2;Ubiquitin carboxyl-terminal hydrolase 2;ubiquitin specific peptidase 2;Ubiquitin specific processing protease 2;Ubiquitin specific protease 12;Ubiquitin specific protease 9;Ubiquitin specific protease;41kD;Ubiquitin thioesterase 2;Ubiquitin thiolesterase 2;Ubiquitin-specific-processing protease 2;Ubiquitin-specific-processing protease testis;UBP-t;UBP2;UBP41;USP2;USP9
UNIProt ID:
O75604