UPF1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-13000
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-13000-20uL20uL£125.00
Quantity:
E-AB-13000-60uL60uL£172.00
Quantity:
E-AB-13000-120uL120uL£237.00
Quantity:
E-AB-13000-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Raji cell using UPF1 Polyclonal Antibody at dilution of 1:300
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Immunohistochemistry of paraffin-embedded Human liver cancer using UPF1 Polyclonal Antibody at dilution of 1:35
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Immunohistochemistry of paraffin-embedded Human thyroid cancer using UPF1 Polyclonal Antibody at dilution of 1:35
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Western Blot analysis of Raji cell using UPF1 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human liver cancer using UPF1 Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human thyroid cancer using UPF1 Polyclonal Antibody at dilution of 1:35

Documents

Further Information

Abbreviation:
UPF1
Background:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in botHuman, MouseRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
124kDa
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human UPF1
Purification method:
Affinity purification
Target Synonym:
ATP dependent helicase RENT1;ATP-dependent helicase RENT1;Delta helicase;FLJ43809;FLJ46894;HUPF 1;hUpf1;KIAA0221;Nonsense mRNA reducing factor 1;NORF 1;NORF1;pNORF 1;pNORF1;Regulator of nonsense transcripts 1;RENT 1;RENT1;RENT1;Smg 2;Smg 2 homolog nonsense mediated mRNA decay factor;UP Frameshift 1;Up frameshift mutation 1 homolog (S. cerevisiae);Up frameshift mutation 1 homolog;Up frameshift suppressor 1 homolog;Up-frameshift suppressor 1 homolog;UPF 1;UPF 1 regulator of nonsense transcripts homolog;upf1;UPF1 regulator of nonsense transcripts homolog;UPF1 RNA helicase and ATPase;Yeast Upf1p homolog
UNIProt ID:
Q92900