UCP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17510-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17510-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17510-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17510-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
UCP1
Background:
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-150, ELISA 1:2000-10000
Immunogen:
Synthetic peptide of human UCP1
Purification method:
Affinity purification
Target Synonym:
UCP;SLC25A7
UNIProt ID:
P25874