TYR Polyclonal Antibody

Elabscience
Product Code: E-AB-10669
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10669-20uL20uL£125.00
Quantity:
E-AB-10669-60uL60uL£172.00
Quantity:
E-AB-10669-120uL120uL£237.00
Quantity:
E-AB-10669-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

1 / 2
Western Blot analysis of A375, Hela and Jurkat cell using TYR Polyclonal Antibody at dilution of 1:600
2 / 2
Immunohistochemistry of paraffin-embedded Skin tissue using TYR Polyclonal Antibody at dilution of 1:100 (Elabscience Product Detected by Lifespan).

Western Blot analysis of A375, Hela and Jurkat cell using TYR Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Skin tissue using TYR Polyclonal Antibody at dilution of 1:100 (Elabscience Product Detected by Lifespan).

Documents

Further Information

Abbreviation:
TYR
Background:
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
60kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-200
Immunogen:
Recombinant protein of human TYR
Purification method:
Affinity purification
Target Synonym:
ATN;CMM8;LB24 AB;LB24-AB;Monophenol monooxygenase;OCA1;OCA1A;OCAIA;Oculocutaneous albinism IA;SHEP3;SK29 AB;SK29-AB;Tumor rejection antigen AB;TYR;TYRO;tyrosinase (oculocutaneous albinism IA);Tyrosinase
UNIProt ID:
P14679

References

  • https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c00582
  • https://www.koreascience.or.kr/article/JAKO202025164428524.page