beta Tubulin Polyclonal Antibody
Code | Size | Price |
---|
E-AB-20070-30uL | 30uL | £125.00 |
Quantity:
E-AB-20070-60uL | 60uL | £146.00 |
Quantity:
E-AB-20070-120uL | 120uL | £196.00 |
Quantity:
E-AB-20070-200uL | 200uL | £216.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
Tubulin β
Background:
TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
50kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen:
Synthesized peptide derived from the C-terminal region of mouse Tubulin β
ObservedMW:
55kDa
Purification method:
Affinity purification
Target Synonym:
beta 3 tubulin;beta-4;CDCBM;CDCBM1;CFEOM3;CFEOM3A;FEOM3;M(beta)3;M(beta)6;MC1R;Neuron specific beta III Tubulin;Neuron-specific class III beta-tubulin;QccE-11995;QccE-15186;TBB3;Tubb 3;TUBB3;TUBB4;Tubulin beta 3;Tubulin beta 3 chain;Tubulin beta 4;Tubulin beta III;Tubulin beta-3 chain;Tubulin beta-4 chain;Tubulin beta-III
UNIProt ID:
Q13509
References
- https://www.tandfonline.com/doi/abs/10.1080/15548627.2022.2052460
- https://www.sciencedirect.com/science/article/pii/S0014299923001188
- https://www.jbc.org/content/294/51/19723.short
- https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.5081
- https://pubs.acs.org/doi/abs/10.1021/acschemneuro.8b00680
- https://iovs.arvojournals.org/article.aspx?articleid=2770345
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013794/