TRAF3 Polyclonal Antibody

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Elabscience
Product Code: E-AB-12665
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-12665-20uL20uL£125.00
Quantity:
E-AB-12665-60uL60uL£172.00
Quantity:
E-AB-12665-120uL120uL£237.00
Quantity:
E-AB-12665-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human fetal kidney tissue using TRAF3 Polyclonal Antibody at dilution of 1:500
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Immunohistochemistry of paraffin-embedded Human ovarian cancer using TRAF3 Polyclonal Antibody at dilution of 1:40
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Immunohistochemistry of paraffin-embedded Human lung cancer using TRAF3 Polyclonal Antibody at dilution of 1:40
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Western Blot analysis of Human fetal kidney tissue using TRAF3 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human ovarian cancer using TRAF3 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer using TRAF3 Polyclonal Antibody at dilution of 1:40

Documents

Further Information

Abbreviation:
TRAF3
Background:
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
64kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human TRAF3
Purification method:
Affinity purification
Target Synonym:
CAP 1;CAP-1;CAP1;CD40 associated protein 1;CD40 binding protein;CD40 bp;CD40 receptor associated factor 1;CD40 receptor-associated factor 1;CD40-binding protein;CD40BP;CRAF 1;CRAF1;IIAE5;LAP 1;LAP1;LMP1 associated protein;LMP1-associated protein 1;MIPT3;TNF receptor associated factor 3;TNF receptor-associated factor 3;TRAF 3;Traf3;TRAF3
UNIProt ID:
Q13114