TPX2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17129-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17129-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17129-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17129-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TPX2
Background:
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
86 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-2000, ELISA 1:2000-5000
Immunogen:
Fusion protein of human TPX2
Purification method:
Affinity purification
Target Synonym:
C20ORF1;C20orf2;Chromosome 20 Open Reading Frame 1;Differentially expressed in cancerous and non-cancerous lung cells 2;Differentially expressed in cancerous and noncancerous lung cells 2;Differentially expressed in lung cells 2;Differentially expressed in lung cells;DIL 2;DIL-2;DIL2;FLS353;GD:C20orf1;HCA 519;HCA519;HCTP 4;HCTP4;Hepatocellular carcinoma associated antigen 519;Hepatocellular carcinoma-associated antigen 519;p100;Preferentially expressed in colorectal cancer;Protein fls353;REPP 86;repp86;Restricted expression proliferation associated protein 100;Restricted expression proliferation-associated protein 100;Targeting protein for Xklp2;TPX 2;TPX2;TPX2 microtubule associated homolog;TPX2 microtubule associated protein homolog;TPX2 microtubule nucleation factor;TPX2
UNIProt ID:
Q9ULW0