TPO Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14412-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14412-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14412-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14412-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TPO
Background:
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human TPO
Purification method:
Affinity purification
Target Synonym:
MSA;PERT;TDH2A;Thyroid microsomal antigen;Thyroid peroxidase;Thyroperoxidase;TPO;TPX
UNIProt ID:
P07202