TP53INP1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-13485
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-13485-20uL20uL£125.00
Quantity:
E-AB-13485-60uL60uL£172.00
Quantity:
E-AB-13485-120uL120uL£237.00
Quantity:
E-AB-13485-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human fetal liver tissue, 293T and 231 cell using TP53INP1 Polyclonal Antibody at dilution of 1:200
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Immunohistochemistry of paraffin-embedded Human brain using TP53INP1 Polyclonal Antibody at dilution of 1:50
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Immunohistochemistry of paraffin-embedded Human prostate cancer using TP53INP1 Polyclonal Antibody at dilution of 1:50
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Immunohistochemistry of paraffin-embedded Liver tissue using TP53INP1 Polyclonal Antibody at dilution of 1:50(Elabscience Product Detected by Lifespan).
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Western Blot analysis of Human fetal liver tissue, 293T and 231 cell using TP53INP1 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human brain using TP53INP1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human prostate cancer using TP53INP1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Liver tissue using TP53INP1 Polyclonal Antibody at dilution of 1:50(Elabscience Product Detected by Lifespan).

Documents

Further Information

Abbreviation:
TP53INP1
Background:
TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
27kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human TP53INP1
Purification method:
Affinity purification
Target Synonym:
DKFZp434M1317;FLJ22139;p53 damage inducible nuclear protein 1;p53 dependent damage inducible nuclear protein 1;p53 inducible nuclear protein 1;p53 inducible p53DINP1;p53-dependent damage-inducible nuclear protein 1;p53DINP1;SIP;Stress induced protein;Stress-induced protein;T53I1;Teap;TP53 DINP1;TP53 INP1;TP53DINP1;TP53INP1;TP53INP1A;TP53INP1B;Tumor protein p53 inducible nuclear protein 1;Tumor protein p53-inducible nuclear protein 1
UNIProt ID:
Q96A56