TNXB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16089-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16089-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16089-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16089-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TNXB
Background:
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human TNXB
Purification method:
Affinity purification
Target Synonym:
EDS3;Ehlers Danlos like syndrome;Growth inhibiting protein 45;Hexabrachion like protein;Hexabrachion-like protein;HXBL;NXB2;Tenascin X precursor;Tenascin XB;Tenascin XB1;Tenascin XB2;Tenascin-X;TENX;TENX;TN X;TN-X;TNX;TNXB;TNXB1;TNXB2;TNXBS;VUR8;XB;XBS
UNIProt ID:
P22105