TNK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12226-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12226-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12226-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12226-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TNK2
Background:
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
119kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human TNK2
Purification method:
Affinity purification
Target Synonym:
Acetate kinase 1;Acetokinase 1;ACK 1;ACK;ACK-1;ACK1;ACK1;Activated Cdc42 associated kinase 1;Activated CDC42 kinase 1;Activated p21cdc42Hs kinase;FLJ44758;FLJ45547;p21cdc42Hs;TNK 2;TNK2;Tyrosine kinase non receptor 2;Tyrosine kinase non receptor protein 2;Tyrosine kinase non-receptor protein 2
UNIProt ID:
Q07912