TNFRSF11B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10508-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10508-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10508-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10508-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TNFRSF11B
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
46kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human TNFRSF11B
Purification method:
Affinity purification
Target Synonym:
MGC29565;OCIF;OPG;Osteoclastogenesis inhibitory factor;Osteoprotegerin;PDB5;TNF receptor superfamily member 11b;TNFRSF 11B;TNFRSF11B;TR 1;TR1;TR11B;Tumor necrosis factor receptor superfamily member 11B
UNIProt ID:
O00300
References
- https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.14218
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367655/