TLR5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14647-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14647-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14647-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14647-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TLR5
Background:
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human TLR5
Purification method:
Affinity purification
Target Synonym:
FLJ10052;MGC126430;MGC126431;SLEB1;TIL 3;TIL3;TLR 5;Tlr5;TLR5;Toll like receptor 5;Toll like receptor 5 precursor;Toll-like receptor 5;Toll/interleukin 1 receptor like protein 3;Toll/interleukin-1 receptor-like protein 3
UNIProt ID:
O60602