TIRAP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17096-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17096-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17096-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17096-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TIRAP
Background:
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-100, ELISA 1:2000-5000
Immunogen:
Full length fusion protein
Purification method:
Affinity purification
Target Synonym:
Adapter protein wyatt;FLJ42305;MAL;MyD88 adapter like protein;TIR domain containing adapter protein;Toll interleukin 1 receptor (TIR) domain containing adaptor protein;Toll interleukin 1 receptor domain containing adapter protein;Toll like receptor adaptor protein;Wyatt
UNIProt ID:
P58753