TGF β Receptor II Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-33088-20uL | 20uL | £125.00 |
Quantity:
| E-AB-33088-60uL | 60uL | £172.00 |
Quantity:
| E-AB-33088-120uL | 120uL | £237.00 |
Quantity:
| E-AB-33088-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TGFβ RII
Background:
TGFBR2 (Transforming Growth Factor BetaReceptor2) is a Protein Coding gene. Diseases associated withTGFBR2 includeLoeys-Dietz Syndrome 2andEsophageal Cancer. Among its related pathways areSMAD2/3 MH2 Domain Mutants in CancerandExtracellular vesicle-mediated signaling in recipient cells. GO annotations related to this gene includetransferase activity, transferring phosphorus-containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isACVR2B.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
65kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Immunogen:
Synthesized peptide derived from the Internal region of human TGFβ RII
ObservedMW:
65kDa
Purification method:
Affinity purification
Target Synonym:
AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;TbetaR II;TbetaR-II;TGF beta receptor type 2;TGF beta receptor type II;TGF beta receptor type IIB;TGF beta type II receptor;TGF-beta receptor type II;TGF-beta receptor type-2;TGF-beta type II receptor;TGF-beta-R2;TGFB R2;TGFbeta - RII;TGFbeta RII;Tgfbr2;TGFR-2;TGFR2;Transforming growth factor beta receptor II;Transforming growth factor beta receptor type II;Transforming growth factor beta receptor type IIC;Transforming growth factor;beta receptor II (70/80kDa);transforming growth factor;beta receptor II alpha;transforming growth factor;beta receptor II beta;transforming growth factor;beta receptor II delta;transforming growth factor;beta receptor II epsilon;transforming growth factor;beta receptor II gamma;Transforming growth factor-beta receptor type II
UNIProt ID:
P37173
References
- https://www.nature.com/articles/s41467-022-35262-w
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006815/