TERT Polyclonal Antibody

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Elabscience
Product Code: E-AB-12512
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-12512-20uL20uL£125.00
Quantity:
E-AB-12512-60uL60uL£172.00
Quantity:
E-AB-12512-120uL120uL£237.00
Quantity:
E-AB-12512-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human fetal liver tissue using TERT Polyclonal Antibody at dilution of 1:200
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Immunohistochemistry of paraffin-embedded Human breast cancer using TERT Polyclonal Antibody at dilution of 1:35
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Western Blot analysis of Human fetal liver tissue using TERT Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human breast cancer using TERT Polyclonal Antibody at dilution of 1:35

Documents

Further Information

Abbreviation:
TERT
Background:
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
127kDa
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human TERT
Purification method:
Affinity purification
Target Synonym:
CMM9;DKCA2;DKCB4;EST2;HEST2;htert;hTRT;PFBMFT1;TCS1;Telomerase associated protein 2;Telomerase catalytic subunit;Telomerase reverse transcriptase;Telomerase-associated protein 2;Telomere Reverse Transcriptase;TERT;TERT;TP2;TRT
UNIProt ID:
O14746