TEK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12907-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12907-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12907-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12907-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TEK
Background:
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smootHuman, Mouseuscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human TEK
Purification method:
Affinity purification
Target Synonym:
Angiopoietin 1 receptor;Angiopoietin-1 receptor;CD202b;CD202b antigen;Endothelial tyrosine kinase;Endothelium specific receptor tyrosine kinase 2;hTIE 2;hTIE2;Hyk;p140 TEK;Soluble TIE2 variant 1;Soluble TIE2 variant 2;Tek;tek tyrosine kinase;TEK tyrosine kinase endothelial;tek tyrosine kinase;endothelial;TIE 2;TIE2;TIE2;Tunica interna endothelial cell kinase;Tyrosine kinase with Ig and EGF homology domains 2;Tyrosine kinase with Ig and EGF homology domains-2;Tyrosine protein kinase receptor TEK;Tyrosine protein kinase receptor TIE 2;Tyrosine-protein kinase receptor TEK;Tyrosine-protein kinase receptor TIE-2;Venous malformations multiple cutaneous and mucosal;VMCM 1;VMCM;VMCM1
UNIProt ID:
Q02763