TBC1D4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13723-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13723-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13723-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13723-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TBC1D4
Background:
TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
147kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150
Immunogen:
Synthetic peptide of human TBC1D4
Purification method:
Affinity purification
Target Synonym:
Acrg embryonic lethality (mouse) minimal region ortholog;Acrg embryonic lethality minimal region ortholog;Acrg embryonic lethality mouse minimal region ortholog;Akt substrate of 160 kDa;AS 160;AS160;BUB2;CDC16;KIAA0603;NIDDM5;TBC (Tre 2 BUB2 CDC16) domain containing protein;TBC Tre 2 BUB2 CDC16 domain containing protein;TBC1 D4;TBC1 domain family member 4;Tbc1d4;TBCD4;Tre-2
UNIProt ID:
O60343