TAB3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15187-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15187-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15187-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15187-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
TAB3
Background:
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
79kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human TAB3
Purification method:
Affinity purification
Target Synonym:
MAP3K7IP 3;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NAP1;NF-kappa-B-activating protein 1;NFkB activating protein 1;TAB-3;Tab3;TAB3;TAK1 binding protein 3;TAK1-binding protein 3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;TGF-beta-activated kinase 1-binding protein 3
UNIProt ID:
Q8N5C8