DRAK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14744-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14744-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14744-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14744-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
STK17B
Background:
The full-lengthSTK17BcDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A andSTK17Bshare 59.7% amino acid identity.Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human STK17B
Purification method:
Affinity purification
Target Synonym:
DAP kinase related apoptosis inducing protein;DAP kinase related apoptosis inducing protein kinase 2;DAP kinase-related apoptosis-inducing protein kinase 2;Death associated protein kinase related 2;DRAK 2;DRAK2;Serine/threonine kinase 17b;Serine/threonine kinase 17b apoptosis inducing;Serine/threonine protein kinase 17B;Serine/threonine-protein kinase 17B;ST17B;STK 17B;Stk17b
UNIProt ID:
O94768