STAT6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10059-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10059-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10059-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10059-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
STAT6
Background:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
94kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human STAT6
Purification method:
Affinity purification
Target Synonym:
12S1644;D12S1644;IL 4 STAT;IL-4 Stat;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;Signal transducer and activator of transcription 6;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;Signal transducer and activator of transcription 6;interleukin 4 induced;STAT 6;STAT interleukin4 induced;STAT;interleukin4 induced;Stat6;STAT6;STAT6B;STAT6C;Transcription factor IL 4 STAT
UNIProt ID:
P42226