STAT5A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13825-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13825-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13825-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13825-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
STAT5A
Background:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
91kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human STAT5A
Purification method:
Affinity purification
Target Synonym:
Mammary gland factor;MGF;Signal transducer and activator of transcription 5A;STA5A;STAT 5;STAT 5A;STAT5;STAT5A
UNIProt ID:
P42229
References
- https://link.springer.com/article/10.1186/s12943-017-0639-2