STAR Polyclonal Antibody
Code | Size | Price |
---|
E-AB-15419-20uL | 20uL | £125.00 |
Quantity:
E-AB-15419-60uL | 60uL | £172.00 |
Quantity:
E-AB-15419-120uL | 120uL | £237.00 |
Quantity:
E-AB-15419-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
STAR
Background:
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
32kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human STAR
Purification method:
Affinity purification
Target Synonym:
Cholesterol trafficker;Luteinizing hormone induced protein;mitochondrial;Mitochondrial steroid acute regulatory protein;StAR;StAR related lipid transfer (START) domain containing 1;STAR;StARD1;START domain containing 1;START domain containing protein 1;START domain-containing protein 1;Steroid acute regulatory protein;Steroidogenic acute regulator;Steroidogenic acute regulatory protein;Steroidogenic acute regulatory protein mitochondrial
UNIProt ID:
P49675
References
- https://www.mdpi.com/1422-0067/22/15/8094
- https://www.frontiersin.org/articles/10.3389/fendo.2020.00302/full
- https://www.mdpi.com/954398
- https://onlinelibrary.wiley.com/doi/abs/10.1002/jez.2609