SPDEF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10535-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10535-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10535-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10535-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SPDEF
Background:
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human SPDEF
Purification method:
Affinity purification
Target Synonym:
bA375E1.3;PDEF;Prostate derived Ets factor;PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR;Prostate epithelium-specific Ets transcription factor;Prostate specific Ets;Prostate-derived Ets factor;Prostate-specific Ets;PSE;RP11-375E1__A.3;SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR;SAM pointed domain-containing Ets transcription factor;Spdef;SPDEF
UNIProt ID:
O95238