SPAST Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16442-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16442-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16442-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16442-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SPAST
Background:
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human SPAST
Purification method:
Affinity purification
Target Synonym:
ADPSP;FSP 2;FSP2;KIAA1083;Spast;spastic paraplegia 4 (autosomal dominant;spastin);Spastic paraplegia 4;spastin;SPG 4;SPG4;SPG4 gene
UNIProt ID:
Q9UBP0