SOCS7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15856-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15856-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15856-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15856-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SOCS7
Background:
The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human SOCS7
Purification method:
Affinity purification
Target Synonym:
Ash and phospholipase C gamma-binding protein;NAP 4;NAP 4 Fragment;NAP-4;NAP4;Nck;Nck Ash and phospholipase C binding protein;Nck Ash and phospholipase C gamma binding protein;Nck associated protein 4;Nck-associated protein 4;NCKAP4;SH2 domain containing SOCS box protein;SOCS 7;SOCS-7;SOCS4;SOCS6;Socs7;SOCS7;Suppressor of cytokine signaling 7
UNIProt ID:
O14512