SOCS2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14356-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14356-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14356-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14356-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SOCS2
Background:
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human SOCS2
Purification method:
Affinity purification
Target Synonym:
CIS 2;CIS-2;CIS2;Cish 2;Cish2;Cytokine inducible SH2 protein 2;Cytokine-inducible SH2 protein 2;SOCS 2;SOCS-2;Socs2;SOCS2;SSI 2;SSI-2;SSI2;STAT induced STAT inhibitor 2;STAT-induced STAT inhibitor 2;STATI 2;STATI2;Suppressor of cytokine signaling 2
UNIProt ID:
O14508