SNCA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13070-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13070-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13070-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13070-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SNCA
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SNCA
Purification method:
Affinity purification
Target Synonym:
Alpha synuclein;Alpha-synuclein;Alpha-synuclein;isoform NACP140;alphaSYN;MGC105443;MGC110988;MGC127560;MGC64356;NACP;Non A beta component of AD amyloid;Non A4 component of amyloid;Non A4 component of amyloid precursor;Non-A beta component of AD amyloid;Non-A-beta component of alzheimers disease amyloid;precursor of;Non-A4 component of amyloid precursor;Non-A4 component of amyloid;precursor of;OTTHUMP00000218549;OTTHUMP00000218551;OTTHUMP00000218552;OTTHUMP00000218553;OTTHUMP00000218554;PARK 1;PARK 4;PARK1;PARK4;Parkinson disease (autosomal dominant;Lewy body) 4;Parkinson disease familial 1;SNCA;Snca synuclein;alpha (non A4 component of amyloid precursor);SYN;Synuclein alpha;Synuclein alpha 140;Synuclein;alpha (non A4 component of amyloid precursor);SYUA
UNIProt ID:
P37840