SMG8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12757-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12757-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12757-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12757-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SMG8
Background:
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SMG8
Purification method:
Affinity purification
Target Synonym:
ABC 2;ABC2;Amplified in breast cancer gene 2 protein;Chromosome 17 open reading;chromosome 17 open reading frame 71;FLJ10587;Protein smg 8 homolog;protein SMG8;SMG8;SMG8 protein
UNIProt ID:
Q8ND04