SMAD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-32916-20uL | 20uL | £125.00 |
Quantity:
| E-AB-32916-60uL | 60uL | £172.00 |
Quantity:
| E-AB-32916-120uL | 120uL | £237.00 |
Quantity:
| E-AB-32916-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Smad2
Background:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
52kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human Smad2 around the non-phosphorylation site of Ser250.
ObservedMW:
52kDa
Purification method:
Affinity purification
Target Synonym:
Drosophila;homolog of;MADR2;hMAD-2;HsMAD2;JV18;JV18-1;JV181;MAD;MAD homolog 2;MAD Related Protein 2;Mad-related protein 2;MADH2;MADR2;MGC22139;MGC34440;Mother against DPP homolog 2;Mothers against decapentaplegic homolog 2;Mothers against decapentaplegic;Drosophila;homolog of;2;Mothers against DPP homolog 2;OTTHUMP00000163489;Sma and Mad related protein 2;Sma- and Mad-related protein 2 MAD;SMAD 2;SMAD family member 2;SMAD;mothers against DPP homolog 2;SMAD2;SMAD2
UNIProt ID:
Q15796