SLC7A11 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17625-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17625-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17625-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17625-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SLC7A11
Background:
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
55 kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:20-100, ELISA 1:2000-5000
Immunogen:
Synthetic peptide of human SLC7A11
Purification method:
Affinity purification
Target Synonym:
Amino acid transport system xc xCT;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Calcium channel blocker resistance protein CCBR1;CCBR1;Cysteine/glutamate transporter;Cystine/glutamate transporter;OTTHUMP00000164578;SLC7A11;Solute carrier family 7 (anionic amino acid transporter light chain;xc- system);member 11;solute carrier family 7;Solute carrier family 7 member 11;Solute carrier family 7;(cationic amino acid transporter;y+ system) member 11;SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN;xCT;XCT
UNIProt ID:
Q9UPY5