SLC6A4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16233-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16233-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16233-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16233-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SLC6A4
Background:
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human SLC6A4
Purification method:
Affinity purification
Target Synonym:
5 HTT;5 HTTLPR;5 hydroxytryptamine (serotonin) transporter;5 hydroxytryptamine transporter;5HT transporter;5HTT;hSERT;HTT;Na+/Cl- dependent serotonin transporter;OCD1;SC6A4;Serotonin transporter 1;SERT;SERT1;Slc6a4;Sodium dependent serotonin transporter;Sodium-dependent serotonin transporter;Solute carrier family 6 (neurotransmitter transporter) member 4;solute carrier family 6 (neurotransmitter transporter;serotonin);member 4;Solute carrier family 6 member 4
UNIProt ID:
P31645