SLC22A17 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16061-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16061-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16061-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16061-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SLC22A17
Background:
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
56kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SLC22A17
Purification method:
Affinity purification
Target Synonym:
24p3 receptor;24p3R;BOCT;BOIT;Brain type organic cation transporter;Brain-type organic cation transporter;hBOIT;Lipocalin-2 receptor;Neutrophil gelatinase associated lipocalin receptor;Neutrophil gelatinase-associated lipocalin receptor;NGAL receptor;NgalR;NGALR2;NGALR3;OTTHUMP00000082690;OTTHUMP00000082691;Potent brain type organic ion transporter;S22AH;Slc22a17;Solute carrier family 22 member 17;Solute carrier family 22 organic cation transporter member 17
UNIProt ID:
Q8WUG5