SIGLEC5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11046-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11046-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11046-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11046-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SIGLEC5
Background:
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human SIGLEC5
Purification method:
Affinity purification
Target Synonym:
CD170;CD170 antigen;CD33 antigen-like 2;CD33L2;mSiglec-F;OB-binding protein 2;OB-BP2;OBBP2;Obesity-binding protein 2;Sialic acid binding Ig-like lectin 5;Sialic acid binding immunoglobulin-like lectin 5;Sialic acid-binding Ig-like lectin 5;Sialic acid-binding Ig-like lectin F;SIGL5;Siglec-5;Siglec-F variant;Siglec5;Siglecf
UNIProt ID:
O15389