SETD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14627-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14627-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14627-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14627-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SETD2
Background:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human SETD2
Purification method:
Affinity purification
Target Synonym:
EC 2.1.1.43;FLJ16420;FLJ22472;FLJ23184;FLJ45883;HBP231;HIF 1;HIF-1;HIF1;HIP-1;Histone lysine N methyltransferase SETD2;Histone-lysine N-methyltransferase SETD2;hSET2;HSPC069;Huntingtin interacting protein 1;Huntingtin interacting protein;Huntingtin interacting protein B;Huntingtin interacting protein HYPB;Huntingtin yeast partner B;Huntingtin-binding protein;231-KD;Huntingtin-interacting protein 1;Huntingtin-interacting protein B;HYPB;KIAA1732;KMT3A;Lysine N methyltransferase 3A;Lysine N-methyltransferase 3A;p231HBP;SET domain containing 2;SET domain-containing protein 2;SET2;SETD2;SETD2
UNIProt ID:
Q9BYW2