SERPINB8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15386-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15386-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15386-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15386-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SERPINB8
Background:
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150
Immunogen:
Recombinant protein of human SERPINB8
Purification method:
Affinity purification
Target Synonym:
CAP 2;CAP-2;CAP2;Cytoplasmic antiproteinase 2;OTTHUMP00000067000;OTTHUMP00000067001;Peptidase inhibitor 8;PI 8;PI-8;PI8;Protease inhibitor 8 (ovalbumin type);Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8;Serpin B8;Serpin peptidase inhibitor clade B (ovalbumin) member 8;Serpinb8;SPB8
UNIProt ID:
P50452