SERPINB5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14208-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14208-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14208-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14208-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SERPINB5
Background:
Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
42kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human SERPINB5
Purification method:
Affinity purification
Target Synonym:
Maspin;Ovalbumin;Peptidase inhibitor 5;PI-5;PI5;protease inhibitor 5 (maspin);Protease inhibitor 5;Serine (or cysteine) peptidase inhibitor;clade B;member 5;serine (or cysteine) proteinase inhibitor;clade B (ovalbumin);member 5;Serpin B5;serpin family B member 5;Serpin peptidase inhibitor;Serpin peptidase inhibitor;clade B (ovalbumin);member 5;Serpinb5;SPB5;Spi5;Spi7
UNIProt ID:
P36952