SDHB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16795-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16795-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16795-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16795-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SDHB
Background:
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
32kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SDHB
Purification method:
Affinity purification
Target Synonym:
CWS2;DHSB;FLJ92337;Ip;Iron sulfur subunit;Iron sulfur subunit of complex II;Iron-sulfur subunit of complex II;mitochondrial;PGL 4;PGL4;SDH 1;SDH;SDH1;SDH2;SDH2;homolog of;SdhB;SDHIP;Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial;Succinate dehydrogenase [ubiquinone] iron sulfur subunit;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit;succinate dehydrogenase [ubiquinone] iron-sulfur subunit;mitochondrial;Succinate Dehydrogenase 1 Iron Sulfur Subunit;Succinate Dehydrogenase 2;S. cerevisiae;homolog of;Succinate dehydrogenase complex iron sulfur subunit B;Succinate dehydrogenase complex subunit B iron sulfur;Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein;succinate dehydrogenase complex;subunit B;iron sulfur (Ip);Succinate dehydrogenase iron sulfur protein
UNIProt ID:
P21912