SCN5A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12860-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12860-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12860-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12860-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
SCN5A
Background:
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SCN5A
Purification method:
Affinity purification
Target Synonym:
Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit;CDCD2;CMD1E;CMPD2;HB1;HB2;HBBD;HH1;ICCD;IVF;LQT3;PFHB1;Scn5a (gene name);Scn5a;SCN5A;Sodium channel protein cardiac muscle alpha subunit;Sodium channel protein cardiac muscle subunit alpha;Sodium channel protein type 5 subunit alpha;Sodium channel protein type V alpha subunit;Sodium channel protein type V subunit alpha;SSS1;VF1;Voltage gated sodium channel alpha subunit Nav1.5;Voltage-gated sodium channel subunit alpha Nav1.5
UNIProt ID:
Q14524