RUNX2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-30103
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-30103-20uL20uL£125.00
Quantity:
E-AB-30103-60uL60uL£172.00
Quantity:
E-AB-30103-120uL120uL£237.00
Quantity:
E-AB-30103-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of K562 cells with RUNX2 Polyclonal Antibody.
2 / 2
Immunofluorescence analysis of Human stomach tissue using RUNX2 Polyclonal Antibody at dilution of 1:200.
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Western Blot analysis of K562 cells with RUNX2 Polyclonal Antibody.
Immunofluorescence analysis of Human stomach tissue using RUNX2 Polyclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
RUNX2
Background:
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
57kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000
Immunogen:
Synthesized peptide derived from the Internal region of human RUNX2.
ObservedMW:
56kDa
Purification method:
Affinity purification
Target Synonym:
Acute myeloid leukemia 3 protein;Alpha subunit 1;AML3;CBF alpha 1;CBF-alpha-1;CBFA1;CCD;CCD1;Cleidocranial dysplasia 1;Core binding factor;Core binding factor runt domain alpha subunit 1;Core binding factor subunit alpha 1;Core-binding factor subunit alpha-1;MGC120022;MGC120023;Oncogene AML 3;Oncogene AML-3;OSF 2;OSF-2;OSF2;Osteoblast specific transcription factor 2;Osteoblast-specific transcription factor 2;OTTHUMP00000016533;PEA2 alpha A;PEA2-alpha A;PEA2aA;PEBP2 alpha A;PEBP2-alpha A;PEBP2A1;PEBP2A2;PEBP2aA;PEBP2aA1;Polyomavirus enhancer binding protein 2 alpha A subunit;Polyomavirus enhancer-binding protein 2 alpha A subunit;Runt domain;Runt related transcription factor 2;Runt-related transcription factor 2;RUNX2;RUNX2;SL3 3 enhancer factor 1 alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;SL3/AKV core binding factor alpha A subunit;SL3/AKV core-binding factor alpha A subunit
UNIProt ID:
Q13950

References

  • https://www.sciencedirect.com/science/article/pii/S0006295222003781
  • https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12973
  • https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.14218