RRM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14316-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14316-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14316-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14316-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RRM1
Background:
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
90kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human RRM1
Purification method:
Affinity purification
Target Synonym:
R1;Ribonucleoside diphosphate reductase large subunit;Ribonucleoside diphosphate reductase M1 chain;Ribonucleoside diphosphate reductase subunit M1;Ribonucleoside reductase;large subunit;Ribonucleoside-diphosphate reductase large subunit;Ribonucleoside-diphosphate reductase subunit M1;Ribonucleotide reductase large chain;Ribonucleotide reductase large subunit;Ribonucleotide reductase M1;Ribonucleotide reductase M1 polypeptide;Ribonucleotide reductase R1 subunit;Ribonucleotide reductase;M1 subunit;RIR 1;RIR1;RIR1;RR 1;RR1;RRM 1;RRM1
UNIProt ID:
P23921