RRAD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16047-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16047-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16047-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16047-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
RRAD
Background:
The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human RRAD
Purification method:
Affinity purification
Target Synonym:
GTP binding protein RAD;GTP-binding protein RAD;RAD;RAD;RAD1;RAS (RAD and GEM) like GTP binding 3;Ras associated with diabetes;Ras related associated with diabetes;REM3;RRAD
UNIProt ID:
P55042