ROR1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16872-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16872-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16872-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16872-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ROR1
Background:
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human ROR1
Purification method:
Affinity purification
Target Synonym:
dJ537F10.1;Inactive tyrosine protein kinase transmembrane receptor ROR1;MGC99659;Neurotrophic tyrosine kinase;Neurotrophic tyrosine kinase receptor related 1;Neurotrophic tyrosine kinase;receptor related 1;NTRKR1;OTTHUMP00000010573;OTTHUMP00000010574;OTTMUSP00000008344;Receptor tyrosine kinase like orphan receptor 1;receptor-related 1;RGD1559469;ROR 1;ROR1;ROR1;RP11 24J23.1;Tyrosine kinase like orphan receptor 1;Tyrosine protein kinase transmembrane receptor ROR1;Tyrosine-protein kinase transmembrane receptor ROR1
UNIProt ID:
Q01973